7,8-Dihydroxyflavone (10mg/capsule), 60 Capsules

Description

High-Purity 7,8-Dihydroxyflavone (10mg/capsule) 60 Capsules: Industrial-Grade Bulk Supply

Procuring high-purity neurochemical reagents and monomeric flavones is essential for advanced neurobiological research, synaptic plasticity assays, and industrial biochemical applications. registeredpeptides.co provides industrial-grade 7,8-Dihydroxyflavone (10mg/capsule, 60 Capsules per unit) engineered to meet large-scale commercial procurement requirements.

We support chemical distributors, enterprise laboratories, and bulk purchasers who demand precise chemical characterization, lot-to-lot consistency, verified purity metrics, and dependable supply chain logistics.

Key Specifications & Chemical Profile

• Chemical Name: 7,8-Dihydroxy-2-phenyl-4H-chromen-4-one

• Synonyms: 7,8-DHF, Tropoflavin

• CAS Number: 38183-03-8

• Molecular Formula: $\text{C}_{15}\text{H}_{10}\text{O}_4$

• Molecular Weight: $254.24\text{ g/mol}$

• Concentration: 10mg active material per capsule

• Quantity: 60 capsules per bottle / Bulk master pack availability

• Purity Rating: Verified $\ge 98\%$ via High-Performance Liquid Chromatography (HPLC)

• Grade: High-purity industrial, commercial, and laboratory reference standard

Compound Overview & Technical Mechanism

7,8-Dihydroxyflavone (7,8-DHF) is a naturally occurring polyphenolic flavone derivative that acts as a potent, small-molecule agonist of the Tropomyosin receptor kinase B (TrkB). Unlike macro-protein brain-derived neurotrophic factor (BDNF), which suffers from poor oral bioavailability and a short plasma half-life, 7,8-DHF exhibits robust blood-brain barrier permeability and stable pharmacokinetic activity.

In biochemical and neurochemical assay models, 7,8-DHF selectively binds to the extracellular domain of TrkB receptors, inducing receptor dimerization, autophosphorylation, and downstream activation of the MAPK/ERK, PI3K/Akt, and PLC$\gamma$1 signaling cascades. The 10mg capsule format provides uniform active content, eliminating measurement variance and particle segregation during high-throughput trial preparations.

What Industrial Chemical Users Look For

When commercial procurement officers, industrial chemists, and laboratory directors source bulk 7,8-DHF inventory, core specifications include:

1. Verified Purity & Analytical Validation: Analytical documentation using High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to confirm sequence identity and absence of heavy metals or residual synthesis solvents.

2. Encapsulation Uniformity: Strict mass fill controls to guarantee exact milligram accuracy across all production units.

3. Scalable Master Order Fulfillments: High-volume inventory access to ensure continuous project operations without supply disruption.

4. Packaging & Storage Integrity: Hermetically sealed, light-impermeable containers that shield polyphenol groups against oxidation, moisture, and photodegradation.

5. Chain-of-Custody Logistics: Secure, temperature-monitored domestic shipping pipelines maintaining raw compound stability.

Key Applications in Research & Industrial Settings

• TrkB Receptor Phosphorylation Assays: Measuring activation kinetics of TrkB pathways in neuronal cell cultures.

• Synaptic Plasticity & Memory Models: Evaluating long-term potentiation (LTP) and dendritic spine density in neurobiological research.

• Neuroprotection Screening: Assessing cellular survival under oxidative stress, excitotoxicity, and ischemic injury conditions.

• Flavonoid Derivative Comparative Analysis: Serving as a baseline reference standard in high-throughput chemical screening for novel TrkB ligands.

Bulk Ordering and Quality Assurance

registeredpeptides.co provides commercial clients direct access to high-grade industrial chemical supply supported by batch-specific analytical testing. Every production lot of 7,8-Dihydroxyflavone 10mg Capsules undergoes comprehensive third-party testing to uphold strict quality standards.

To obtain current batch Certificates of Analysis (COA), inquire about custom packaging options, or secure tiered volume pricing for bulk orders, contact our chemical supply division today.