Sunifiram – powder, 10 grams

High-Purity Sunifiram Powder (10 Grams): Industrial-Grade Bulk Supply

Procuring high-potency AMPAkines and piperazine-derived research compounds requires verified chemical structure, ultra-pure crystalline consistency, and full analytical characterization. registeredpeptides.co supplies industrial-grade Sunifiram Powder (10 Grams) engineered to support scalable enterprise procurement, high-throughput bio-assays, and institutional research protocols.

We support chemical distributors, enterprise laboratories, and high-volume purchasers who demand strict chemical specifications, verified purity profiles, and dependable supply chain logistics.

Key Specifications & Chemical Profile

• Chemical Name: 1-(4-benzoylpiperazin-1-yl)propan-1-one

• Synonyms: DM-235

• CAS Number: 314728-85-3

• Molecular Formula: $\text{C}_{14}\text{H}_{18}\text{N}_2\text{O}_2$

• Molecular Weight: $246.31\text{ g/mol}$

• Unit Format: 10 Grams (Pure Crystalline Solid / Raw Powder)

• Purity Rating: Verified $\ge 98\%$ via High-Performance Liquid Chromatography (HPLC)

• Grade: High-purity industrial, commercial, and laboratory reference standard

Compound Overview & Technical Mechanism

Sunifiram (DM-235) is a synthetic alkaloid derivative structurally related to the racetam class, featuring a modified piperazine core in place of the classic pyrrolidone ring. Developed as a highly potent AMPAkine, Sunifiram acts as a positive allosteric modulator of $\alpha$-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) receptors.

In laboratory, electrophysiological, and biochemical research, Sunifiram displays a distinct neuro-modulatory mechanism:

• AMPA Receptor Potentiation: Enhances glutamate-mediated AMPA receptor signaling without direct agonist binding, facilitating synaptic transmission and long-term potentiation (LTP) in hippocampal slices.

• Glycine Site NMDA Activation: Indirectly enhances NMDA receptor activation via glycine binding site stimulation, promoting intracellular calcium influx in active post-synaptic neurons.

• Acetylcholine Release Stimulation: Increases pre-frontal cortex acetylcholine efflux, serving as a primary model agent for investigating cross-talk between glutamatergic and cholinergic networks.

The 10-gram pure raw powder format offers maximum operational flexibility for preparing customized stock solutions, analytical reference standards, and automated screening protocols.

What Industrial Chemical Users Look For

When commercial procurement managers, industrial chemists, and laboratory directors source bulk Sunifiram powder and raw chemical inventory, core specifications include:

1. Verified Chemical Purity & COA Document: Complete lot characterization via Mass Spectrometry (MS), NMR, and HPLC to confirm exact molecular structure and freedom from unreacted intermediates or heavy metals.

2. Scalable Wholesale Supply: Uninterrupted supply chain pipelines capable of providing bulk raw powder shipments for industrial formulation and contract research.

3. Crystalline Stability & Humidity Control: Processed and packaged under controlled atmospheric conditions to prevent moisture absorption, physical clumping, or chemical degradation.

4. Batch-to-Batch Uniformity: Strict quality control standards ensuring identical melting point, solubility profiles, and particle size distribution across all production lots.

5. Chain-of-Custody Logistics: Secure domestic shipping pipelines with moisture-proof, UV-protected packaging to guarantee compound integrity upon arrival.

Key Applications in Research & Industrial Settings

• AMPA & Glutamate Receptor Kinetics: Measuring positive allosteric modulation velocity and synaptic response amplitudes in neuronal tissue cultures.

• Hippocampal Long-Term Potentiation (LTP) Studies: Evaluating synaptic plasticity markers and electrophysiological potential shifts in cortical slices.

• Neurotransmitter Cross-Talk Assays: Quantifying cortical acetylcholine release rates secondary to AMPA receptor activation.

• Analytical Method Validation: Utilizing pure 10-gram reference standards for developing HPLC and LC-MS/MS quantitative detection protocols.

Bulk Ordering and Quality Assurance

registeredpeptides.co provides commercial clients and research facilities direct access to high-grade chemical supply backed by batch-specific analytical testing. Every production lot of Sunifiram Powder (10 Grams) undergoes third-party testing to uphold strict quality control standards.

To request current batch Certificates of Analysis (COA), inquire about custom bulk packaging, or secure tiered volume pricing, contact our chemical distribution team today.