High-Purity Industrial Grade Letrozole (1mg / 60 Capsules)

Letrozole is a potent third-generation non-steroidal aromatase inhibitor belonging to the triazole derivative class. Formulated at a precise active concentration of 1mg per capsule across a 60-capsule commercial container, this chemical compound is manufactured for institutional laboratories, endocrinology research centers, and pharmaceutical testing workflows. Produced under strict quality assurance standards, each batch delivers the chemical stability, mass accuracy, and structural purity required for advanced enzymatic inhibition assays and steroidogenesis studies.

For industrial procurement managers, university laboratories, and contract research organizations seeking dependable chemical supply across Canada, peptidesprocanada.com provides full batch traceability, secure packaging, and efficient nationwide logistics.

Key Technical Specifications and Chemical Identity

• Chemical Name: 4,4′-(1H-1,2,4-triazol-1-ylmethylene)dibenzonitrile

• IUPAC Name: 4-[[4-cyanophenyl)-(1,2,4-triazol-1-yl)methyl]benzonitrile

• Molecular Formula: $C_{17}H_{11}N_5$

• Molecular Mass: 285.31 g/mol

• CAS Registry Number: 112809-51-5

• Active Content: 1mg active ingredient per capsule

• Container Quantity: 60 encapsulated units per bottle

• Purity Assay: Equal to or greater than 98.0% (quantified via HPLC)

• Solubility: Soluble in organic solvents such as dichloromethane, dimethyl sulfoxide (DMSO), and ethanol; sparingly soluble in water

Requirements for Industrial and Laboratory Buyers

Procurement specialists and research directors evaluating enzymatic inhibitors and active triazole compounds require verified technical standards prior to issuing purchase orders:

1. Analytical Certificates and Purity Verification: Every production run undergoes High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) to verify molecular mass, active concentration uniformity (1mg per unit), and absence of synthetic residual impurities. Comprehensive Certificates of Analysis (COA) accompany all bulk orders.

2. Batch Consistency and Dose Uniformity: Automated micro-encapsulation ensures precise mass distribution, eliminating intra-capsule dosage variance and enabling reliable high-throughput assay calibration.

3. Environmental Safeguards and Storage Stability: Letrozole is sensitive to atmospheric humidity and photolytic exposure. Units are sealed in light-impermeable, UV-resistant containers equipped with desiccant inserts and induction heat seals to maximize shelf stability.

4. Supply Chain Integrity: Robust handling and delivery protocols ensure material stability throughout transit across all Canadian provinces.

5. Regulatory Compliance and SDS Availability: Complete Safety Data Sheets (SDS) outlining physical chemical properties, workplace safe-handling procedures, personal protective measures, and waste disposal protocols are provided.

Primary Industrial and Biochemical Research Applications

Letrozole is widely recognized as a benchmark compound in bio-organic chemistry, oncology research, and reproductive endocrinology:

• Aromatase Enzyme ($text{CYP19A1}$) Inhibition Assays: Evaluated in competitive enzymatic assays to study competitive binding to the heme component of the cytochrome P450 unit of aromatase, blocking the conversion of androgens to estrogens.

• Estrogen Suppression Kinetics: Used in cellular models to measure intracellular estradiol and estrone level suppression without impacting adrenocortical steroidogenesis or aldosterone synthesis.

• Hormone-Dependent Oncology Modeling: Serves as a primary reference agent in evaluating estrogen-receptor-positive ($text{ER}^+$) cell proliferation, gene transcription downstream effects, and drug resistance mechanisms.

• Folliculogenesis and Ovulation Signaling Research: Analyzed in reproductive biology studies examining gonadotropin feedback loops, follicle-stimulating hormone (FSH) sensitivity, and ovarian steroidogenesis pathways.

Commercial Bulk Orders and Logistics

We manage commercial orders and ongoing contract logistics for research laboratories, university facilities, and industrial buyers throughout Canada. Tiered volume pricing, batch reservations, and flexible delivery arrangements are available to accommodate institutional supply schedules.

To submit purchase orders, request Safety Data Sheets, or download batch COAs for Letrozole (1mg/60 capsules), visit peptidesprocanada.com and contact our chemical sales team.