Description

High-Purity Industrial Grade Raloxifene (20mg / 60 Capsules)

Raloxifene is a non-steroidal selective estrogen receptor modulator (SERM) belonging to the benzothiophene class. Formulated at a precise concentration of 20mg per capsule in a 60-capsule commercial container, this active chemical compound is manufactured for institutional laboratories, endocrine research facilities, and industrial pharmaceutical testing workflows. Produced under strict quality control protocols, each batch provides the chemical consistency, mass accuracy, and structural integrity required for advanced receptor assays and cellular signaling studies.

For industrial procurement managers, university laboratories, and contract research organizations seeking dependable chemical supply across Canada, peptidesprocanada.com provides complete batch traceability, robust packaging, and efficient nationwide logistics.

Key Technical Specifications and Chemical Identity

Chemical Name: [6-hydroxy-2-(4-hydroxyphenyl)benzo[b]thiophen-3-yl][4-[2-(piperidin-1-yl)ethoxy]phenyl]methanone
IUPAC Name: [6-hydroxy-2-(4-hydroxyphenyl)-1-benzothiophen-3-yl]-[4-(2-piperidin-1-ylethoxy)phenyl]methanone
Molecular Formula: $C_{28}H_{27}NO_4S$ (Free Base) / $C_{28}H_{28}ClNO_4S$ (Hydrochloride Salt)
Molecular Mass: 473.58 g/mol (Free Base) / 510.04 g/mol (HCL Salt)
CAS Registry Number: 84449-90-1 (Free Base) / 84449-89-8 (Hydrochloride Salt)
Active Content: 20mg active material per capsule
Container Quantity: 60 encapsulated units per bottle
Purity Assay: Equal to or greater than 98.0% (quantified via HPLC)
Solubility: Soluble in dimethyl sulfoxide (DMSO), sparingly soluble in ethanol, and practically insoluble in water

Requirements for Industrial and Laboratory Buyers

Procurement officers evaluating active small molecules and selective receptor ligands require verified quality and workplace safety compliance before placing bulk orders:

Analytical Testing and COA Verification: Every production lot undergoes High-Performance Liquid Chromatography (HPLC) and Mass Spectrometry (MS) testing to confirm chemical identity, active content uniformity (20mg per unit), and absence of synthetic impurities. Complete Certificates of Analysis (COA) accompany every bulk shipment.
Dose Uniformity and Mass Tolerance: Manufactured using precise micro-encapsulation machinery, ensuring tight batch consistency and zero intra-capsule variance for high-throughput screening and assay calibration.
Environmental Protection and Shelf Stability: Raloxifene is sensitive to excessive moisture and light exposure. Packaged in UV-resistant containers equipped with induction seals and desiccants to maintain raw chemical stability over extended storage periods.
Supply Chain Security: Standardized handling and shipping protocols ensure material integrity during transit across all Canadian provinces.
Regulatory Compliance and SDS Availability: Comprehensive Safety Data Sheets (SDS) detailing chemical characteristics, handling guidelines, personal protective equipment requirements, and waste management procedures are provided.

Primary Industrial and Biochemical Research Applications

Raloxifene is widely utilized as a benchmark compound in molecular pharmacology, oncology research, and tissue-specific receptor dynamics:

Estrogen Receptor Alpha ( $text{ER}alpha$ ) and Beta ( $text{ER}beta$ ) Binding Assays: Investigated for its tissue-specific agonist and antagonist activities, acting as an antagonist in mammary and uterine tissue while exhibiting agonist activity in bone tissue pathways.
Bone Density and Mineralization Modeling: Utilized in osteoblast and osteoclast cell line cultures to study TGF- $beta3$ gene expression and inhibition of bone resorption signaling pathways.
Oncology and Mammary Cell Line Research: Serves as a primary reference agent in evaluating estrogen-dependent cell proliferation, apoptosis induction, and cell cycle arrest mechanisms.
Lipid Metabolism and Cardiovascular Marker Assays: Evaluated in metabolic research to study serum lipid profiles, LDL oxidation rates, and vascular endothelial response markers.

Commercial Bulk Orders and Supply Logistics

We fulfill commercial purchasing needs and ongoing chemical supply contracts for institutional facilities throughout Canada. Custom volume pricing, batch reservations, and flexible delivery schedules are available to meet institutional demand.

To request a custom bulk quote, download Safety Data Sheets, or review batch COAs for Raloxifene (20mg/60 capsules), visit peptidesprocanada.com and contact our chemical logistics team.