Pregnenolone – Powder, 5 grams

Description

High-Purity Pregnenolone Powder (5 Grams): Industrial-Grade Bulk Supply

Procuring high-purity steroid precursors and neurosteroid active chemical ingredients requires precise chemical characterization, strict crystalline consistency, and full analytical verification. registeredpeptides.co supplies industrial-grade Pregnenolone Powder (5 Grams) engineered to support scalable enterprise procurement, pilot-plant synthesis, and institutional laboratory research protocols.

We support chemical distributors, enterprise laboratories, and high-volume purchasers who demand strict chemical specifications, verified purity profiles, and dependable supply chain logistics.

Key Specifications & Chemical Profile

• Chemical Name: 3$\beta$-hydroxypregn-5-en-20-one

• CAS Number: 145-13-1

• Molecular Formula: $\text{C}_{21}\text{H}_{32}\text{O}_2$

• Molecular Weight: $316.48\text{ g/mol}$

• Unit Format: 5 Grams (Pure Crystalline Solid / Raw Powder)

• Purity Rating: Verified $\ge 98\%$ via High-Performance Liquid Chromatography (HPLC) / GC-MS

• Grade: High-purity industrial, commercial, and laboratory reference standard

Compound Overview & Technical Mechanism

Pregnenolone is an endogenous progestogen and neurosteroid that serves as the major progestagen precursor for all downstream steroid hormones, including mineralocorticoids, glucocorticoids, androgens, and estrogens. Synthesized from cholesterol via the mitochondrial cytochrome P450 side-chain cleavage enzyme (CYP11A1), it occupies a central node in steroidogenesis.

In laboratory, metabolic, and neurochemical research, Pregnenolone displays a complex mechanism profile:

• Endogenous Steroid Biosynthesis Precursor: Acts as the fundamental substrate in enzymatic conversion pathways leading to progesterone, DHEA, cortisol, and aldosterone.

• Neurosteroid & Allosteric Modulation: Modulates central nervous system signaling as a negative allosteric modulator of $\text{GABA}_\text{A}$ receptors and a positive allosteric modulator of NMDA receptors.

• Microtubule-Associated Protein Interaction: Binds directly to microtubule-associated protein 2 (MAP2), stimulating tubulin assembly and promoting dendritic elongation and synaptic remodeling.

The 5-gram pure raw powder format offers maximum flexibility for customized solubilization, analytical standard preparation, and high-throughput enzymatic assay calibration.

What Industrial Chemical Users Look For

When commercial procurement managers, industrial chemists, and laboratory directors source bulk Pregnenolone powder and steroid chemical inventory, core specifications include:

1. Verified Chemical Purity & COA Document: Complete lot characterization via Mass Spectrometry (MS), NMR, and HPLC to confirm exact molecular structure and freedom from unreacted precursors or heavy metals.

2. Scalable Wholesale Supply: Uninterrupted supply chain pipelines capable of providing bulk raw powder shipments for industrial synthesis and contract research.

3. Crystalline Stability & Humidity Protection: Processed and packaged under dry environmental conditions to prevent atmospheric moisture absorption or crystal lattice degradation.

4. Batch-to-Batch Uniformity: Strict quality control standards ensuring identical melting point, particle size distribution, and solubility profiles across all production lots.

5. Chain-of-Custody Logistics: Secure domestic shipping pipelines with moisture-proof, UV-protected packaging to guarantee compound integrity upon arrival.

Key Applications in Research & Industrial Settings

• Steroidogenic Enzyme Kinetics Assays: Mapping 3$\beta$-hydroxysteroid dehydrogenase ($3\beta$-HSD) activity and downstream metabolic turnover rates.

• Neurosteroid Receptor Kinetics: Evaluating allosteric modulation kinetics on NMDA and $\text{GABA}_\text{A}$ receptor complexes in neuronal tissue cultures.

• Cytoskeletal & Microtubule Assembly Dynamics: Analyzing MAP2 binding interactions and dendritic spine structural maintenance in vitro.

• Analytical Method Validation: Utilizing pure 5-gram reference standards for developing HPLC and GC-MS quantitative detection protocols.

Bulk Ordering and Quality Assurance

registeredpeptides.co provides commercial clients and research facilities direct access to high-grade chemical supply backed by batch-specific analytical testing. Every production lot of Pregnenolone Powder (5 Grams) undergoes third-party testing to uphold strict quality control standards.

To request current batch Certificates of Analysis (COA), inquire about custom bulk packaging, or secure tiered volume pricing, contact our chemical distribution team today.