High-Purity Synephrine HCl Powder (20 Grams): Industrial-Grade Bulk Supply

Procuring high-purity adrenergic alkaloids and sympathomimetic research reagents requires structural verification, consistent crystalline formation, and comprehensive analytical documentation. registeredpeptides.co supplies industrial-grade Synephrine HCl Powder (20 Grams) engineered to support scalable enterprise procurement, pilot-plant synthesis, and institutional laboratory research protocols.

We support chemical distributors, enterprise laboratories, and high-volume purchasers who demand strict chemical specifications, verified purity profiles, and dependable supply chain logistics.

Key Specifications & Chemical Profile

Chemical Name: 4-[1-hydroxy-2-(methylamino)ethyl]phenol hydrochloride
Synonyms: p-Synephrine HCl, Oxedrine hydrochloride
CAS Number: 5985-28-4 (HCl Salt) / 94-07-5 (Free Base)
Molecular Formula: $\text{C}_9\text{H}_{14}\text{ClNO}_2$
Molecular Weight: $203.67\text{ g/mol}$
Unit Format: 20 Grams (Pure Crystalline Powder / Hydrochloride Salt Form)
Purity Rating: Verified $\ge 98\%$ via High-Performance Liquid Chromatography (HPLC) / GC-MS
Grade: High-purity industrial, commercial, and laboratory reference standard

Compound Overview & Technical Mechanism

Synephrine HCl is a naturally occurring phenethylamine derivative structurally related to catecholamines and ephedrine alkaloids. Formulated as a stable hydrochloride salt, p-synephrine exhibits optimal aqueous solubility, crystal stability, and resistance to atmospheric oxidation compared to free base alkaloid extractions.

In laboratory, metabolic, and receptor profiling research, Synephrine HCl displays a selective sympathomimetic mechanism:

Selective $\beta_3$ -Adrenergic Agonism: Acts predominantly as a selective agonist at $\beta_3$ -adrenergic receptors, stimulating lipolysis and thermogenesis in adipose cell lines without activating cardiac $\beta_1$ or $\beta_2$ receptors to the degree of classic catecholamines.
Weak $\alpha$ -Adrenergic Binding: Demonstrates minimal binding affinity for $\alpha_1$ and $\alpha_2$ -adrenergic receptors, making it a valuable comparative ligand in cardiovascular and smooth muscle reactivity assays.
Metabolic Rate Modulation: Upregulates basal metabolic rate and cellular substrate oxidation in brown adipocyte and skeletal muscle cell culture models.

The 20-gram raw powder format offers maximum operational flexibility for preparing customized stock solutions, analytical standards, and automated high-throughput assays.

What Industrial Chemical Users Look For

When commercial procurement managers, industrial chemists, and laboratory directors source bulk Synephrine HCl powder and raw chemical inventory, core specifications include:

Verified Chemical Purity & COA Document: Complete lot characterization via Mass Spectrometry (MS), NMR, and HPLC to confirm exact molecular structure, hydrochloride salt conversion efficiency, and freedom from heavy metal or solvent residues.
Scalable Wholesale Supply: Uninterrupted supply chain pipelines capable of providing bulk raw powder shipments for industrial formulation and contract research.
Crystalline Integrity & Hygroscopic Protection: Processed and packaged under controlled atmospheric conditions to prevent moisture absorption, crystal lattice degradation, or clumping.
Batch-to-Batch Uniformity: Strict quality control standards guaranteeing identical melting point, particle size distribution, and solubility profiles across all production lots.
Chain-of-Custody Logistics: Secure domestic shipping pipelines with moisture-proof, UV-protected packaging to guarantee compound integrity upon arrival.

Key Applications in Research & Industrial Settings

Adrenergic Receptor Selectivity Assays: Measuring competitive binding kinetics across $\beta_1$ , $\beta_2$ , and $\beta_3$ receptor subtypes.
Lipolysis & Thermogenesis Studies: Quantifying glycerol release and free fatty acid mobilization in cultured adipocytes.
Comparative AlkaloidSAR Profiling: Serving as a baseline standard in evaluating structure-activity relationships across substituted phenethylamines.
Analytical Method Validation: Utilizing pure 20-gram reference standards for developing HPLC and LC-MS/MS quantitative detection protocols.

Bulk Ordering and Quality Assurance

registeredpeptides.co provides commercial clients and research facilities direct access to high-grade chemical supply backed by batch-specific analytical testing. Every production lot of Synephrine HCl Powder (20 Grams) undergoes third-party testing to uphold strict quality control standards.

To request current batch Certificates of Analysis (COA), inquire about custom bulk packaging, or secure tiered volume pricing, contact our chemical distribution team today.

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Synephrine HCl – Powder, 20 grams