Description

Anastrozole 0.5mg Capsules (60 Capsules)

Potent Third-Generation Non-Steroidal Aromatase Inhibitor

Anastrozole is a potent triazole derivative classified as a third-generation non-steroidal aromatase inhibitor. By reversibly binding to the heme iron of the cytochrome P450 aromatase enzyme ( $text{CYP19A1}$ ), Anastrozole blocks the rate-limiting enzymatic conversion of androgens into estrogens. Renowned across endocrine, biochemical, and pharmacological research, Anastrozole serves as an essential reference standard for studying steroidogenesis inhibition, estrogen receptor cross-talk, and peripheral hormone suppression.

At peptidesprocanada.com, we supply high-volume, industrial-grade chemical compounds manufactured to exact purity standards. Our Anastrozole 0.5mg / 60 Capsules product provides precise micro-gram level dosing, complete mass uniformity, and verified batch-to-batch consistency for institutional research and commercial buyers across Canada.

Key Specifications & Technical Profile

Chemical Name: $2,2'-[5-(1text{H}-1,2,4-text{triazol}-1-text{ylmethyl})-1,3-text{phenylene}]bis(2-text{methylpropanenitrile})$
Synonyms: Anastrozole, ICI-D1033, ZD1033
CAS Number: 120511-73-2
Molecular Formula: $text{C}_{17}text{H}_{19}text{N}_5$
Molecular Weight: $293.37text{ g/mol}$
Dosage Strength: 0.5mg per capsule
Quantity: 60 Capsules per container
Purity Level: $ge 99%$ (HPLC Verified)
Form: Encapsulated Solid Powder
Classification: Non-Steroidal Aromatase Inhibitor (Triazole Derivative)

Key Structural & Biochemical Attributes

Anastrozole exhibits selective enzymatic inhibition without disturbing glucocorticoid or mineralocorticoid pathways in the adrenal gland, distinguishing it from earlier-generation non-selective inhibitors.

Essential attributes for laboratory evaluation and industrial application include:

High Enzymatic Affinity: Exerts potent competitive inhibition at nanomolar concentrations against cytochrome P450 aromatase ( $text{CYP19A1}$ ).
Highly Selective Suppression: Inhibits peripheral estrogen biosynthesis without interfering with cortisol or aldosterone synthesis dynamics.
Chemical Stability: Features a robust nitrile and triazole backbone, providing structural stability in ambient laboratory conditions and analytical solvents.

Quality Requirements for Industrial Chemical Procurement

Commercial buyers, laboratory directors, and chemical distributors demand strict compliance, high purity, and seamless supply chain security. peptidesprocanada.com fulfills every industrial standard:

High-Resolution Analytical Testing (HPLC & MS): Every production run undergoes rigorous assay testing to verify a minimum purity of 99%, ensuring complete freedom from synthesis intermediates or heavy metals.
Micro-Precision Encapsulation: Formulated with automated volumetric micro-dosing systems to guarantee exact 0.5mg active content per capsule.
Complete Technical Documentation: Wholesale shipments include full Certificates of Analysis (CoA) and up-to-date Safety Data Sheets (SDS) for laboratory safety compliance.
Light & Moisture Barrier Protection: Packaged in high-density, UV-resistant pharmaceutical containers to guard light-sensitive triazole linkages against environmental degradation.
Direct Canadian Distribution: Domestic fulfillment from within Canada eliminates international border holds, customs duties, and import delays.

Industrial & Laboratory Applications

Anastrozole is widely utilized in biochemistry, molecular biology, and endocrinology research environments:

Steroidogenesis Pathway Inhibition: Studying the down-regulation of endogenous estradiol and estrone biosynthesis in cellular models.
Aromatase Kinetics & Assays: Serving as a primary reference antagonist in competitive enzyme binding studies.
Endocrine Feedback Mechanisms: Investigating gonadotropin response ( $text{LH}$ and $text{FSH}$ ) following systemic peripheral estrogen reduction.
Comparative Inhibitor Profiling: Benchmarking relative potency against steroidal aromatase inactivators such as Exemestane.

Wholesale & Bulk Procurement in Canada

Whether you need bulk chemical inventory for institutional research projects or commercial distribution networks, peptidesprocanada.com offers competitive wholesale tier pricing, stable stock availability, and tailored order structures.

Purchase your Anastrozole 0.5mg Capsules (60 Capsules) directly from peptidesprocanada.com today to secure verified purity, full documentation, and fast domestic delivery across Canada.